Hello, Welcome to Changzhou Jingzhu Drying Equipment Co., Ltd. Website!

HomeHome Contact usContact us 中文

news

contact us

Changzhou Jingzhu Drying Equipment Co., Ltd.
Add: Sanhekou Industrial Park,Zheng Luzhen,Changzhou City,Jiangsu Province
Tell: 0086-51989627708
  0086-519-89627738
Fax: 0086-519-89627718
Contacts: Lu Huanbiao
Mob: 0086-13861278173
E-mail: jz@jzdry.com


>Your position : Home > News > Industry news

Spray dry type distinction and comparison

Sources : | Release date: 2016-12-14 | View :
Keywords :

Spray dry type distinction and comparison


2.1 spray drying the type of difference
There are many types of spray drying, according to the process can be divided into: open, closed cycle, from the inert circulation and semi-closed cycle; according to spray and gas flow direction is divided into: parallel, counterflow and mixed flow ; According to the atomization method can be divided into: centrifugal, pressure and air flow. Among them, the atomization method classification is commonly used in the way, the following focus on the atomizer.


2.1.1 the role of atomizer
The role of the atomizer is the entire spray of dry heart, it directly affects the product quality and economic indicators. The higher the dispersibility of the atomizer, the greater the drying efficiency; the more uniform the atomization, the smaller the moisture content of the product. Therefore, the atomizer should not only ensure the dispersion of the material, but also to minimize the change in particle size.


2.1.2 "three types" atomizer characteristics


2.1.2.1 Centrifugal atomizer characteristics
Centrifugal atomization: the material in the high-speed turntable (peripheral speed 90 ~ 160m / s) by the centrifugal force from the edge of the disk thrown and atomized. Which is the use of high-speed rotating disk, when the liquid into the disk, the liquid by two kinds of force, one is centrifugal force and gravity under the action of accelerated and split atomization; Second, the liquid and the surrounding air at the same contact, there is friction To promote the formation of droplets. The former is centrifugal atomization, the latter for the speed atomization, in fact the two are coexistence.
The atomization effect of the centrifugal atomizer is directly related to the material characteristics, flow rate, disk shape diameter and speed. Centrifugal atomization process of the "three" features:
① directly split into droplets, when the liquid flow is less, the material by the centrifugal force, around the disc uplift into a hemispherical, its diameter depends on the centrifugal force and liquid viscosity and surface tension. When the centrifugal force is greater than the surface tension, the droplets around the disc are immediately thrown and split atomization.
② filamentous cut into droplets, when the material flow is greater and speed up, the hemispherical material liquid was pulled into a number of filamentous jet. Liquid volume increases, the disk around the liquid also increased, if the amount of liquid reaches a certain number, the liquid wire thicker, and the number of silk no longer increased. Throwing the liquid wire is very unstable, not far away from the periphery that is separated into small spherical droplets.
③ filaments split into droplets, when the material flow continues to increase, the number of silk and silk are no longer increased, the liquid film into a film between each other, throwing liquid from the disk around a certain distance, was split A wide range of droplets. If the liquid on the disc surface can be reduced to the minimum sliding, the liquid can be high-speed jet, in the disc around the air friction and split atomization.


2.1.2.2 Characteristics of pressure type atomizer
Pressure-type atomization: the use of high-pressure pump to get high-pressure liquid, high-pressure liquid through the nozzle, the pressure can be converted into kinetic energy and high-speed spray when dispersed droplets. When the liquid is pressurized from a single hole, it is due to the external force, the liquid from the nozzle outlet not far from the distance, to overcome the surface tension, from the liquid film split into thin lines, plus turbulent radial Speed and the relative speed of the surrounding air, so that the liquid line and then split into different sizes of droplets, pressure atomizer is from the principle of starting.
Pressure atomizer features: ① simple structure, the operation no noise; ② change the internal structure of the nozzle, easy to get the desired atomization shape; ③ large-scale production can be multi-nozzle spray.
Pressure sprayer shortcomings: ① production process can not adjust the flow; ② nozzle nozzle diameter less than 1mm, easy to produce clogging; ③ not suitable for high viscosity of the gel liquid and solid phase decomposition of the spray solution; ④ nozzle easy to wear.


2.1.2.3 Characteristics of airflow atomizer
Airflow atomization (also known as two fluid spray): the use of compressed air at a very high speed from the nozzle (≥ 300 m / s), relying on the difference between the gas and liquid between the two frictional force, For the droplets. The use of steam or compressed air high-speed movement, so that the material at the nozzle outlet to meet the liquid film split and atomization. As the liquid speed is not large, and the air velocity is high, the two fluids have a relative velocity, the liquid film is drawn into a wire, and then split into fine droplets, droplet size depends on the relative speed and liquid viscosity.
Airflow atomization has limitations, only when the hot air temperature is higher than 300 ℃ when the use of steam injection is meaningful, the general use of steam pressure of 0.3-0.7MPa, the use of compressed air pressure of 0.2-0.5MPa, the average droplet diameter Is 10-60 μm.


2.2 Comparison of spray drying with atomizer classification
project
Centrifugal spray
Pressure-type spray airflow spray liquid treatment capacity adjustment range of the largest adjustment range, but the maximum amount of treatment adjustment range narrow viscosity changes can change the speed for high viscosity materials, high viscosity spray difficult to adjust the compressed air pressure Supply pressure (MPa ) Low pressure, about 0.3 high pressure, 1-20 low pressure, about 0.3 high pressure pump do not need to need to pump the pump does not need to atomize the price of high cheap cheap maintenance high-speed rotation of the high precision, easy to wear difficult to wear, high pressure pump to be easy Consumption of small and smallest maximum product size particles coarse particles uniformity uniform uniform uniform uneven accumulation of dense light, the particles in the hole was spherical, the particles in the air content of the dry tower hot air flow to the countercurrent and horizontal flow are not suitable for parallel, countercurrent, mixed Flow and horizontal flow can be co-current, counter-current tower diameter small tower long low high low installation location and sticky wall phenomenon atomizer installed in the top of the tower, the top wall of the wall easy to adhere to the nozzle can be installed in any position, To prevent the diameter of easy to stick type horizontal parallel flow type ● ● vertical upward counter-current ● ● vertical down and flow ● ● ● vertical up mixed flow ● vertical to non-mixed flow ● ●


3. A brief description of the characteristics of several commonly used spray drying equipment
The following combination of one step of the company's several spray drying equipment in the pharmaceutical industry application characteristics, made a brief introduction, can make users have a better understanding, but also a step in the company's products better application and service in the pharmaceutical industry.


3.1LPG high speed centrifugal spray dryer
LPG High Speed Centrifugal Spray Dryers are ideal for the production of powdered, granular or bulk solid products from solutions, emulsions, suspensions and plastic pastes. Therefore, when the finished particle size distribution, residual moisture content, bulk density and particle shape must meet the exact criteria.
The process is as shown in Figure 2, where the air is filtered and heated and dispensed into the drying chamber by the dryer top air distributor. The liquid is sprayed into a very fine mist by a centrifugal atomizer, which is dried in parallel with hot air for a short period of time. The finished product is continuously collected from the bottom of the drying tower and the cyclone, and the exhaust is discharged by the fan.
LPG high-speed centrifugal spray dryer Features:
① drying speed, the material after the atomization of the surface area greatly increased in the hot air flow, the instant can evaporate 95% -98% of the water to complete the drying time only a few seconds, especially for heat-sensitive materials drying.
② products with good uniformity, mobility and solubility, product purity, good quality.
③ production process is simplified, easy to operate and control. For moisture content of 40% -60% of the liquid can be dried into a powder product, dry without grinding and screening, reduce the production process, improve product purity. The product size, bulk density, moisture, can be adjusted by changing the operating conditions, control and management convenience.
LPG high-speed centrifugal spray dryer has been used in Beijing Huafeng Pharmaceutical Co., Ltd., Henan Lingrui Pharmaceutical Co., Ltd., Chinese Academy of Sciences Guangrun Biological Industrial Company, Jilin Weiwei Pharmaceutical Co., Ltd. and Henan Puyang Chinese medicine factory.
 
3.2WPG sterile spray dryer
Figure 3WPG sterile spray dryer aseptic production is the pharmaceutical industry in the production of powder injection equipment, antibiotics such as streptomycin sulfate, kanamycin sulfate, etc., in its production process should use sterile spray drying Manufacturing finished product. In a sterile spray drying system, all materials and air entering the system must be sterilized and filtered. Product collection must also be carried out in the sterile room, the spray with the compressed air also need to be purified before use.
Process flow (Figure 3), the dry air by the initial effect, efficiency, high efficiency three filter purification, heating and material heating and mass transfer material mass transfer, dry after the finished product and hot air separated by the cyclone. The finished product is packed in a sterile chamber cleaning table, and the exhaust is evacuated by a bag filter.
The device uses two fluid air sprayers, simple structure, good air distribution, atomization uniform, can meet the requirements of sterile spray. Spray tower equipped with cleaning device, easy to clean tower wall with powder. Hot air purification selection of early effect, efficiency and efficient three filtration system, so the high quality of air purification, to GMP pharmaceutical production requirements.
3.3ZLG Chinese medicine extract spray dryer
ZLG traditional Chinese medicine extract spray dryer (Figure 4) The machine is fully enclosed, all parts are made of stainless steel, with three purification device, filtered air up to 100,000 requirements. Simplified and top equipped with cooling device, So that the wall temperature of <80 ℃, the material on the tower wall to stay no coking deterioration, increasing the rate of harvest (up to 95%).
Basic principles: Chinese medicine extract High-speed centrifugal spray device is centrifugal spray drying technology in the application of specific materials in the drying, but also the use of high-speed centrifugal atomizer to disperse the material into the mist, with hot air full contact to complete the instant dry, Drying of powdery finished products.
Chinese medicine extract special dryer is the traditional Chinese medicine extract and product extract spray dryer, which solves the material in the original LPG high-speed spray dryer in the traditional Chinese medicine in the following situation: ① material sticky wall, the yield is low; ②, material In the tower wall to stay time to produce coking deterioration; ③ difficult to clean, do not meet the GMP requirements; ④ low yield: LPG-150 spray dryer, the output can only handle 50-60kg / h liquid.
In view of the above situation, our company according to the nature of Chinese medicine extract and process requirements of the design of traditional Chinese medicine extractor dryer, the design of traditional Chinese medicine extract dry granulation process (see Figure 5), dry material color is good, no deterioration, improved Drying equipment using the economic benefits of traditional Chinese medicine extract and LPG high-speed centrifugal spray dryer compared to the following characteristics: ① the use of three air filter cleanliness, reaching 300,000; ② using a cooling device, so that the wall temperature of 80 ℃ , The material on the wall to stay in the filter is not "coking"; ③ the entire volume is the original LPG standard centrifugal spray 3.5 times; ④ use of fast open cleaning device, suitable for multi-species production requirements; ⑤ dust using a wet dust, ⑥ to provide atomizer 2, and the use of frequency control; ⑦ using PLC control, program control system screen display; ⑧ using dry air-tightly closed; ⑦ the use of air-conditioning device, the effect is more satisfactory; delivery.
 
3.4PGL series spray drying granulator
PGL series of B-type / C-type two, PGL-B spray drying granulator set spray drying / fluidization granulation in one, to achieve liquid material one-step granulation; PGL-C spray drying granulator set, spray drying , Granulation, particle coating in one multi-functional.
1) PGL-B spray drying granulator using spray technology, especially for microbial materials, heat-sensitive materials, efficiency than the FL boiling granulator 1-2 times; the final product of up to 0.1% moisture, equipped with powder device, Granulation rate ≥ 95%, can be made 0.2-2mm particles. At the same time, improve the design of the mixed multi-fluid atomizer, can handle the proportion of extract up to 1.3g / cm3.
PGL-B spray drying granulator can be applied to tablets, granules, capsules particles, can also be applied to low-sugar, sugar-free proprietary Chinese medicine particles.
PGL-B spray drying granulator has been in Changzhou Jianmin Pharmaceutical Factory, Chia Taiqing Chunbao Pharmaceutical Co., Ltd., Shanghai Cai Tongde Tong Pharmaceutical Factory, Hunan Jiuzhitang Pharmaceutical Co., Ltd., Hainan Chengcheng Pharmaceutical Co., Ltd., Anhui Phoenix Pine Co., Ltd. Harbin Island Pharmaceutical Co., Ltd. Hebei Pharmaceutical Group Pharmaceutical Co., Ltd. and many other companies use.
2) PGL-C spray drying granulator can be tablets, granules, capsule particles preparation, slow release granule preparation, low sugar, sugar-free, low-dose particles preparation. Preparation of the particles instantly soluble, easy to dissolve granules, easy to disintegrate the tablet, the use of liquid materials as a wetting adhesive, can save a lot of ethanol solvent.
Equipment in the closed negative pressure work, the surface smooth, no dead ends, in line with GMP requirements; the entire dry space temperature uniformity, supporting multi-fluid atomizer, can effectively improve production efficiency and protect product quality; automation has been further improved, simple operation , Can effectively protect the stability of product quality.
 
3.5YPG pressure spray drying granulator
YPG pressure spray drying granulator is the material into the top of the tower at the nozzle of the nozzle into a small droplet droplets, parallel with the top of the hot air to complete the dry. PG pressure spray drying granulator process (such as (Figure 7), the machine has a high dust collection, no sticky wall, energy efficient and so on, especially for heat-sensitive materials such as Chinese medicine extract, medicine glue, yeast, , Antibiotics, amylases, lipases and other dry.
3.6QPG air spray drier
QPG air spray dryer process (such as Figure 8), clean air into the drying tower, in the tower hot air with two fluid (or three fluid) nozzle will be a variety of liquid material into a small droplets, and hot air Rapid heat exchange, evaporation of liquid in the liquid (or solvent), and with hot air discharge, get powder products.
QPG air spray dryer especially on the sticky, paste, paste material effect is good, other equipment can not be replaced. The product is a variety of experimental species, low temperature drying applications. The nozzle structure is simple, easy maintenance, high operating costs.

Relate Articles
Relate Products
  • GMF series of high temperature hot air furnace
    GMF series of high temperature hot air furnace
  • Medicinal GMP oven
    Medicinal GMP oven
  • CSJ coarse grinder
    CSJ coarse grinder
  • GZL series of dry roll granulator
    GZL series of dry roll granulator
  • PGL series spray drying granulator
    PGL series spray drying granulator
  • WZ single effect outer circulation evaporator
    WZ single effect outer circulation evaporator
  • WZ three-effect energy-saving evaporator
    WZ three-effect energy-saving evaporator
  • Stainless steel containers
    Stainless steel containers

Add:Sanhekou Industrial Park,Zheng Luzhen,Changzhou City,Jiangsu Province Tell:0086-519-89627708 0086-519-89627738
Fax:0086-519-89627718 Contacts:LuHuanbiao 0086-13861278173 E-mail:jz@jzdry.com
Copyright © 2017 Changzhou Jingzhu Drying Equipment Co., Ltd. Legalnotice Design : EastNet [Manage]

Top